Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development Running title: Raaz et al.; Segmental aortic stiffening drives AAA formation

نویسندگان

  • Uwe Raaz
  • Alexander M. Zöllner
  • Isabel N. Schellinger
  • Ryuji Toh
  • Futoshi Nakagami
  • Fabian C. Emrich
  • Yosuke Kayama
  • Suzanne Eken
  • Matti Adam
  • Thomas Hertel
  • Alicia Deng
  • Ann Jagger
  • Michael Buerke
  • Ronald L. Dalman
  • Ellen Kuhl
  • Philip S. Tsao
چکیده

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; VA Palo Alto Health Care System, Palo Alto, CA; Dept of Mechanical Engineering, Stanford University School of Medicine, Stanford, CA; Dept of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA; Dept of Medicine, Karolinska Institute, Stockholm, Sweden; Center for Vascular Medicine, Zwickau, Germany; Division of Cardiovascular Medicine and Intensive Care Medicine, Saint Mary’s Hospital, Siegen, Germany; Division of Vascular Surgery, Stanford University School of Medicine, Stanford, CA; Dept of Bioengineering, Stanford University School of Medicine, Stanford, CA

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منابع مشابه

Letter by Murakami et al Regarding Article, "Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development".

BACKGROUND Stiffening of the aortic wall is a phenomenon consistently observed in age and in abdominal aortic aneurysm (AAA). However, its role in AAA pathophysiology is largely undefined. METHODS AND RESULTS Using an established murine elastase-induced AAA model, we demonstrate that segmental aortic stiffening precedes aneurysm growth. Finite-element analysis reveals that early stiffening of...

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Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; VA Palo Alto Health Care System, Palo Alto, CA; Dept of Mechanical Engineering, Stanford University School of Medicine, Stanford, CA; Dept of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA; Dept o...

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Aortic Stiffness and Disease: Location is Key.

I ncreased risk of cardiovascular disease and events associated with aortic stiffening has been attributed both to the hemodynamic consequences of stiffening and to this being a marker for an age-related degeneration of the arterial wall predisposing to arterial disease. 1 There are several measures of arterial stiffness. Indeed, the term stiffness, which does not have a physical definition, wa...

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Drug Therapy for Small Abdominal Aortic Aneurysm

Dear Editor,Abdominal aortic aneurysm is often asymptomatic, less recognized, and causes considerable mortality and morbidity, if missed. The incidence varies from country to country and the occurrence is influenced by modifiable (smoking, coronary heart disease, hypertension, dyslipidemia, and prolonged steroid therapy) and non-modifiable risk factors (increasing age, male gender, and positive...

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Inpatient Mortality Following Repair of Abdominal Aortic Aneurysm in a Tertiary Hospital in Tehran

This study was conducted to monitor the rate of inpatient mortality and its associated factors following open reconstruction of abdominal aortic aneurysm (AAA) in a tertiary hospital in Tehran, Iran. This retrospective study was a chart review of 112 patients undergoing open in­frarenal abdominal aortic aneurysm surgery in one of the main tertiary hospitals in Tehran, Iran. Baseline data (d...

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تاریخ انتشار 2015